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#Unit 3. Fundamental Processes
RNA-induced silencing complex (RISC/RITS) remodeling complexes to chromatin to form heterochromatin in telomeres.
The siRNA complex promotes methylation of histone H3K9 by the Clr4 methyltransferase (also known as KMT1, a homolog of Drosophila Su[Var]3–9). H3K9 methylation recruits the S. pombe homolog of HP1, Swi6.