In cells lacking functional caspase-8 or FADD, TNFα

triggers an alternative pathway, necroptosis.

TLS Online TPP Program

#Id: 3262

#Unit 6. System Physiology – Plant

Amytal (a barbiturate drug), rotenone (a plant product commonly used as an insecticide), and piericidin A (an antibiotic) inhibit electron flow from the Fe-S centers of Complex I to ubiquinone

TLS Online TPP Program

#Id: 3265

#Unit 6. System Physiology – Plant

Protein components of the mitochondrial electron-transfer chain

TLS Online TPP Program

#Id: 3269

#Unit 6. System Physiology – Plant

Agents that interfere with oxidative phosphorylation or photophosphorylation

TLS Online TPP Program

#Id: 3270

#Unit 6. System Physiology – Plant

Complex II as succinate dehydrogenase, the only membrane-bound enzyme in the citric acid cycle

TLS Online TPP Program

#Id: 3274

#Unit 6. System Physiology – Plant

Complex II contains five prosthetic groups and four different protein subunits;
a. Subunits A and B extend into the matrix; they contain three 2Fe-2S centers, bound FAD, and a
binding site for the substrate, succinate
b. Subunits C and D are integral membrane proteins, contain a heme group, heme b, and a binding
site for ubiquinone,

TLS Online TPP Program

#Id: 3275

#Unit 6. System Physiology – Plant

Complex III, also called cytochrome bc1 complex or ubiquinone;