Integrins have an important function in neuroregeneration after injury of the peripheral nervous system.

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#Unit 7. System Physiology – Animal

p75 NTR forms heteromeric complexes with the different Trk receptors and enhances Trk receptor signaling

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#Unit 7. System Physiology – Animal

Schwann cells and astrocytes produce ciliary neurotrophic factor which promotes the survival of damaged and embryonic spinal cord neurons

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A synapse is a site where information is transmitted from one cell to another. 

Types of synapses:

1. electrical synapse

2. chemical synapse

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#Unit 7. System Physiology – Animal

Principle of one-way conduction at chemical synapses 

always transmit the signals in one direction i.e., from the neuron that secretes the neurotransmitter called the presynaptic neuron, to the neuron on which the transmitter acts, called the postsynaptic neuron

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Once an impulse reaches the presynaptic terminals, a response can be obtained in the postsynaptic neuron after a Synaptic delay.

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Synaptic delay is due to the time it takes for the synaptic mediator to be released and to act on the receptors on the membrane of the postsynaptic cell. 

The minimum time for synaptic delay is 0.5 ms