Binding of Wnt to its receptor Frizzled (Fz) and to the LRP co-receptor triggers phosphorylation of LRP by GSK3 and CK1, enables Axin to bind LRP & Dsh.

 

TLS Online TPP Program

#Id: 7966

#Unit 2. Cellular Organization

Binding of BiP to the luminal domain of monomeric Ire1 prevents formation of the Ire1 dimer.

TLS Online TPP Program

#Id: 7967

#Unit 2. Cellular Organization

Hydrolysis of the bound GTP accompanies disassembly of the SRP and SRP receptor and initiates transfer of the nascent chain and ribosome to a site on the ER membrane, where translocation can take place.

TLS Online TPP Program

#Id: 8135

#Unit 2. Cellular Organization

The Golgi consists of four functionally distinct regions:

a. Cis compartments

b. Medial compartments

c. Trans compartments

d. Trans-Golgi network

TLS Online TPP Program

#Id: 8136

#Unit 2. Cellular Organization

Golgi apparatus is a major site of carbohydrate synthesis, as well as a sorting and dispatching station for proteins products.

TLS Online TPP Program

#Id: 8137

#Unit 2. Cellular Organization

In animal cells,

Most of the glycosaminoglycans of the extracellular matrix are synthesized in golgi apparatus.

TLS Online TPP Program

#Id: 8138

#Unit 2. Cellular Organization