The dat locus contains DnaA-binding sites that titrate availability of DnaA protein.

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#Unit 8. Inheritance Biology

At the end of a normal chromosome 9 is a potential cancer-causing gene called c- ABL.   As a result of the translocation, part of the cABL gene is fused with the BCR gene from chromosome 22. The protein produced by this BCR–c-ABL fusion gene is much more active than the protein produced by the normal c- ABL gene.

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#Unit 8. Inheritance Biology

TLS Online TPP Program

#Id: 6967

#Unit 8. Inheritance Biology

Burkitt lymphoma Burkitt lymphoma possess a reciprocal translocation between chromosome 8 and chromosome 2, 14, or 22.  This translocation relocates a gene called c-MYC is next to a gene that encodes an immunoglobulin protein.

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#Unit 8. Inheritance Biology

TLS Online TPP Program

#Id: 6969

#Unit 8. Inheritance Biology

Aneuploidy

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#Unit 8. Inheritance Biology

Aneuploidy can arise in several ways

Chromosome may be lost during mitosis or meiosis.

The small chromosome generated by a Robertsonian translocation may be lost in mitosis or meiosis.

Aneuploidy may arise through nondisjunction.