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TLS Online TPP Program

#Id: 1776

In the presence of antigen and TGF-β, CD8+ regulatory T cells expressing FoxP3 can be induced (iTREG).

#Unit 4. Cell Communication and Cell Signaling #Hypersensitivity and autoimmunity #Part B Pointers
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TLS Online TPP Program

#Id: 6925

#Unit 8. Inheritance Biology

Deletions are lethal in the homozygous state because all copies of any essential genes located in the deleted region are missing.
TLS Online TPP Program

#Id: 6926

#Unit 8. Inheritance Biology

Heterozygous condition may produce imbalances in the amounts of gene products similar to those produced by extra gene copies.
TLS Online TPP Program

#Id: 6927

#Unit 8. Inheritance Biology

Pseudodominance - Recessive allele owing to a deletion on the homologous chromosome.
TLS Online TPP Program

#Id: 6928

#Unit 8. Inheritance Biology

Haploinsufficiency - One copy of the gene is missing; a mutant phenotype is produced
TLS Online TPP Program

#Id: 6929

#Unit 8. Inheritance Biology

Deletions can be detected cytologically by studying the banding patterns in stained chromosomes. 
TLS Online TPP Program

#Id: 6930

#Unit 8. Inheritance Biology

Large aberrations can be detected by examination of mitotic chromosomes that have been stained with banding agents such as quinacrine or Giemsa.