Highest rates of substitutions in regions of the gene that have the least effect on function, such as the third position of a codon, flanking regions, and introns.

TLS Online TPP Program

#Id: 8354

#Unit 2. Cellular Organization

Listeria is a food-borne bacterial pathogen has on its surface a protein ActA, which mimics an NPF that efficiently activates the Arp2/3 complex.

TLS Online TPP Program

#Id: 8356

#Unit 2. Cellular Organization

ActA protein binds the host protein VASP, which enhance actin assembly and confine it to the rear of the bacterium.

TLS Online TPP Program

#Id: 8357

#Unit 2. Cellular Organization

VASP 

has a proline-rich

hold onto the end of the newly formed filament

protect the end of the growing filament from CapZ

TLS Online TPP Program

#Id: 8358

#Unit 2. Cellular Organization

On Endosomes 

Arp2/3-dependent nucleation of actin filament by An NPF is WASH

TLS Online TPP Program

#Id: 8359

#Unit 2. Cellular Organization

In Golgi complex

Arp2/3-dependent assembly of actin occur by an NPF WHAMM participating in membrane traffic from the ER to golgi

TLS Online TPP Program

#Id: 8360

#Unit 2. Cellular Organization