Blocking the activities of gyrase and topoisomerase therefore result in major changes in DNA supercoiling, which in turn affects transcription and replication.

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#Unit 13. Methods in Biology

There are two types of probability distribution which are used for different purposes and various types of the data generation process.

a. Normal or Cumulative Probability Distribution

b. Binomial or Discrete Probability Distribution

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#Unit 13. Methods in Biology

The cumulative probability distribution is also known as a continuous probability distribution. In this distribution, the set of possible outcomes can take on values in a continuous range.

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#Unit 13. Methods in Biology

Cumulative Probability Distribution

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#Unit 13. Methods in Biology

A distribution is called a discrete probability distribution, where the set of outcomes are discrete in nature.

For example, if a dice is rolled, then all the possible outcomes are discrete and give a mass of outcomes. It is also known as the probability mass function.

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#Unit 13. Methods in Biology

So, the outcomes of binomial distribution consist of n repeated trials and the outcome may or may not occur. The formula for the binomial distribution is;

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#Unit 13. Methods in Biology

The probability distribution of a statistic, from a particular population, over many random samples is the sampling distribution.