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TLS Online TPP Program

#Id: 3198


Errors in replication and damage to DNA have two consequences;
One is, of course, the introduction of permanent changes to the DNA (mutations), which can alter the coding sequence of a gene or its regulatory sequences.
The second consequence is that some chemical alterations to the DNA prevent its use as a template for replication and transcription

#Unit 3. Fundamental Processes #DNA damage and repair mechanisms #Part B Pointers
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TLS Online TPP Program

#Id: 6392

#Unit 2. Cellular Organization

Stimulation of b-galactosidase synthesis by cAMP with wild-type and mutant CAP.


TLS Online TPP Program

#Id: 6393

#Unit 2. Cellular Organization

The E. coli trp operon contains the 5 genes Trp-EDCBA for the anabolic enzymes to make the tryptophan.

TLS Online TPP Program

#Id: 6394

#Unit 2. Cellular Organization

Major enzyme is Tryptophan Synthase



TLS Online TPP Program

#Id: 6395

#Unit 2. Cellular Organization

Major enzyme is Tryptophan Synthase whose activity is reduced when trp concentration is high

TLS Online TPP Program

#Id: 6396

#Unit 2. Cellular Organization

Trp operon is negatively regulated by two ways
 Repression
Attenuation

TLS Online TPP Program

#Id: 6397

#Unit 2. Cellular Organization

Why is this extra control of two layers on trp operon needed?  The answer probably lies in the fact that repression of the trp operon is weak—much weaker.

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