TLS Online TPP Program

#Id: 3294


Ubiquinone (Q) is reduced by four ways;
a. By the oxidation of NADH in complex I
b. Electrons from succinate pass through a flavoprotein with the cofactor FAD and several Fe-S
centers (in Complex II) on the way to Q
c. Glycerol 3-phosphate donates electrons to a flavoprotein (glycerol 3-phosphate dehydrogenase)
on the outer face of the inner mitochondrial membrane, from which they pass to Q.
d. Acyl-CoA dehydrogenase (the first enzyme of oxidation) transfers electrons to electron-
transferring flavoprotein (ETF), from which they pass to Q via ETF


#Unit 6. System Physiology – Plant #Plant Mitochondrial Electron Transport #Part B Pointers
More Pointers
TLS Online TPP Program

#Id: 5905

#Unit 3. Fundamental Processes

Enzymes responsible for PTJ Helicase is hexameric and motor that melts the duplex and requires ATP hydrolysis—typically 1 ATP is hydrolyzed for each base pair that is unwound.

TLS Online TPP Program

#Id: 5906

#Unit 3. Fundamental Processes

Each DNA helicase moves along ssDNA in a defined direction. This property is referred to as the polarity of the DNA helicase. DNA helicases can have a polarity of either 5’->3’ or 3’->5’.

TLS Online TPP Program

#Id: 5907

#Unit 3. Fundamental Processes

In the case of a DNA helicase that functions on the lagging-strand template of the replication fork, the polarity is 5’->3’ to allow the DNA helicase to proceed toward the duplex region of the replication fork The PhiX system, named originally for phage X174, requires an initiation complex consisting of additional components, called the primosome. This system is used when damage causes the replication fork to collapse and it must be restarted.




TLS Online TPP Program

#Id: 5908

#Unit 3. Fundamental Processes

E. coli SSB is a tetramer of 74 kD that binds single-stranded DNA cooperatively

TLS Online TPP Program

#Id: 5909

#Unit 3. Fundamental Processes

A common feature of all DNA polymerases is that they cannot initiate synthesis of a chain of DNA de novo, but can only elongate a chain.

TLS Online TPP Program

#Id: 5910

#Unit 3. Fundamental Processes

The 3’–OH end is called a primer.
A sequence of RNA is synthesized on the template, so that the free 3’–OH end of the RNA chain is extended by DNA Pol and This is commonly used in replication of cellular DNA and by some viruses.
In case of reteroviruses, A preformed RNA (often a tRNA) pairs with the template, allowing its 3’–OH end to be used to prime DNA synthesis.