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Fructose 2,6-bisphosphate binds to its allosteric site on PFK-1, it increases the enzyme’s affinity for its substrate fructose 6-phosphate and reduces its affinity for the allosteric inhibitors ATP and citrate


#Unit 1. Molecules and their Interaction Relevant to Biology #Metabolism #Part B Pointers
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#Unit 2. Cellular Organization

The entire process of mitotic CDKs activation and entry into mitosis involves two positive feedback loops and coordination between events at the centrosome, in the cytoplasm, and in the nucleus.

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#Unit 13. Methods in Biology

The most commonly used general protein stain for detecting protein on gels is the sulfated trimethylamine dye Coomassie Brilliant Blue R-250 (CBB).


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#Unit 7. System Physiology – Animal

Between heartbeats, influx of positively charged sodium ions causes a slow rise in the resting membrane potential in the positive direction. 



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#Unit 2. Cellular Organization

CDK- Cyclin in Metazoans-
G1 Phase- cyclin D–CDK4/6
G1/S Phase- cyclin E–CDK2
S Phase- cyclin A–CDK2
M Phase- cyclin A/B–CDK1

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#Unit 3. Fundamental Processes

the origin has been opened (and the DNA is single-stranded) by its ability to further unwind the DNA.

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