#Id: 3412
SOS response in E. coli:
When DNA is extensively damaged (such as by UV light), DNA replication is halted and the number of single-strand gaps in the DNA increases.
RecA protein binds to this damaged, single-stranded DNA, activating the protein’s co-protease activity.
While bound to DNA, the RecA protein facilitates cleavage and inactivation of the LexA repressor. When the repressor is inactivated, the SOS genes, including RecA, are induced;

#Unit 3. Fundamental Processes
#DNA damage and repair mechanisms
#Part B Pointers