The fivefold discrepancy in size between the S. cerevisiae (84 kb) and mammalian (16.6 kb) mitochondrial genomes indicates the fact that there must be a great difference in their genetic organization in spite of their common function.

TLS Online TPP Program

#Id: 10053

#Unit 4. Cell Communication and Cell Signaling

γ-secretase complex contains 

Presenilin 1 (actual protease), aph-1, pen-2, & nicastrin

TLS Online TPP Program

#Id: 10054

#Unit 4. Cell Communication and Cell Signaling

Cleavage by the γ-secretase complex releases the Notch cytosolic segment, which translocates to the nucleus, interacts with a single DNA-binding transcription factor, CSL.

TLS Online TPP Program

#Id: 10055

#Unit 4. Cell Communication and Cell Signaling

Growth factors and EGFs are synthesized as TM proteins, regulated cleavage of the precursor by members of the ADAM protease releases the active molecule into the extracellular space.

TLS Online TPP Program

#Id: 10056

#Unit 4. Cell Communication and Cell Signaling

Cell-adhesion molecules (CAMs) mediate direct cell-cell adhesions.

TLS Online TPP Program

#Id: 10057

#Unit 4. Cell Communication and Cell Signaling

Adhesion receptors mediate cell-matrix adhesions

TLS Online TPP Program

#Id: 10058

#Unit 4. Cell Communication and Cell Signaling

Homophilic Binding 

A CAM on one cell can directly bind to the same kind of CAM on an adjacent cell