When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.

TLS Online TPP Program

#Id: 8532

#Unit 2. Cellular Organization

Catastrophe 

The change from growth to shrinkage

TLS Online TPP Program

#Id: 8533

#Unit 2. Cellular Organization

Rescue 

The change from shrinkage to growth

TLS Online TPP Program

#Id: 8534

#Unit 2. Cellular Organization

γ-tubulin ring complex (γ-TuRC)

nucleates assembly of a microtubule by forming a template corresponding to the (−) end. 

TLS Online TPP Program

#Id: 8535

#Unit 2. Cellular Organization

Augmin

an 8-subunit protein complex that binds to sites along the microtubule and recruits γ-TuRC, which nucleates a new microtubule to form a microtubule branch.

TLS Online TPP Program

#Id: 8536

#Unit 2. Cellular Organization

Plant cells rely extensively on augmin-dependent microtubule branching nucleation to organize the microtubule cytoskeleton because they lack centrosomes.

TLS Online TPP Program

#Id: 8537

#Unit 2. Cellular Organization

Augmin-induced branches help build the spindle during mitosis.