When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.

TLS Online TPP Program

#Id: 2104

#Unit 8. Inheritance Biology

Wolf–Hirschhorn syndrome- Deletion on 4, short arm

TLS Online TPP Program

#Id: 2105

#Unit 8. Inheritance Biology

Williams–Beuren syndrome- Deletion on 7, long arm

TLS Online TPP Program

#Id: 2106

#Unit 8. Inheritance Biology

Prader–Willi syndrome- Deletion on 15 long arm

TLS Online TPP Program

#Id: 2107

#Unit 8. Inheritance Biology

Deletion of a number of pairs that is not evenly divisible by three will lead to a frameshift mutation.

TLS Online TPP Program

#Id: 2108

#Unit 8. Inheritance Biology

In an individual heterozygous for a deletion, the normal chromosome loops out during chromosome pairing in prophase I.

 

TLS Online TPP Program

#Id: 2109

#Unit 8. Inheritance Biology

Deletion includes the centromere, then the chromosome will not segregate in meiosis or mitosis and will usually be lost.