When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.

TLS Online TPP Program

#Id: 6488

#Unit 3. Fundamental Processes

TBP causes the minor groove to be widened to an almost flat conformation; it also bends the DNA by an angle of 80. The interaction between TBP and DNA involves only a limited number of hydrogen bonds between the protein and the edges of the base pairs in the minor groove.  Instead, much of the specificity is imposed by two pairs of phenylalanine side chains that intercalate between the base pairs at either end of the recognition sequence and drive the strong bend in the DNA.

TLS Online TPP Program

#Id: 9253

#Unit 6. System Physiology – Plant

TLS Online TPP Program

#Id: 9826

#Unit 6. System Physiology – Plant

phyA is rapidly degraded as Pfr and controls plant responses to VLFRs and the far-red HIRs.

TLS Online TPP Program

#Id: 6839

#Unit 8. Inheritance Biology

COMPONENTS OF GENETIC VARIANCE

TLS Online TPP Program

#Id: 8924

#Unit 2. Cellular Organization

DNA damage response system

halts cell cycle progression and

recruits DNA repair machinery

when DNA is compromised