Before replication, the palindromic target GATC site is methylated by dam methylase on the N6 of A of each strand.

Replication generates hemimethylated DNA, in which one strand is methylated and one strand is unmethylated.

Thus, the replication event converts Dam target sites from fully methylated to hemimethylated condition.

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#Unit 8. Inheritance Biology

Collaborative gene interaction

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#Unit 8. Inheritance Biology

Comb shapes in chickens

9/16 walnut (R- P-)

3/16 rose (R- pp)

3/16 pea (rr P-)

1/16 single (rr pp)

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#Unit 8. Inheritance Biology

Gene Interaction with Epistasis

The effect of gene interaction is that one gene masks (hides) the effect of another gene at a different locus.

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RECESSIVE EPISTASIS

The recessive allele of one gene hides the expression of all alleles of another gene. Ex- coat color in Labrador retrievers

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Bombay phenotype

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#Unit 8. Inheritance Biology