The first two bases of an mRNA codon always form strong Watson-Crick base pairs with the corresponding bases of the tRNA anticodon and confer most of the coding specificity.

TLS Online TPP Program

#Id: 5899

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 5900

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 5901

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 5902

#Unit 3. Fundamental Processes

The lagging strand must be synthesized in the form of Okazaki fragments of 1000 bp -2000 bp

TLS Online TPP Program

#Id: 5903

#Unit 3. Fundamental Processes

The source of this breakage is the incorporation of some uracil into DNA in place of thymine. When the uracil is removed by a repair system, the leading strand has breaks until a thymine is inserted. Thus, the lagging strand is synthesized discontinuously and the leading strand is synthesized continuously. This is called semidiscontinuous replication.

TLS Online TPP Program

#Id: 5904

#Unit 3. Fundamental Processes

A new model for the structure of the DNA Pol III complex proposes a three-polymerase core structure, with two Pol III catalytic cores responsible for synthesis of the lagging strand and one for the leading strand.