TLS Online TPP Program

#Id: 3719


Repetitive DNA sequences renature faster than non repetitive DNA due to uniformity of sequence

#Unit 2. Cellular Organization #Gene Numbers, Clusters & Repeats #Part B Pointers
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TLS Online TPP Program

#Id: 359

#Unit 1. Structure and Function of Biomolecules

Eukaryotic cells have two isozymes of aconitase
• The mitochondrial isozyme (convert citrate to isocitrate in the citric acid cycle)
• The cytosolic isozyme 

TLS Online TPP Program

#Id: 360

#Unit 1. Structure and Function of Biomolecules

The cytosolic isozymes has two distinct function, It catalyzes the conversion of citrate to isocitrate, providing the substrate for a cytosolic isocitrate dehydrogenase that generates NADPH as reducing power for fatty acid synthesis and other anabolic processes in the cytosol. It also has a role in cellular iron homeostasis

TLS Online TPP Program

#Id: 363

#Unit 1. Structure and Function of Biomolecules

When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.


TLS Online TPP Program

#Id: 364

#Unit 1. Structure and Function of Biomolecules

Pyruvate kinase acts in the nucleus to regulate the transcription of genes that respond to thyroid hormone. Glyceraldehyde 3-phosphate dehydrogenase moonlights both as uracil DNA glycosylase, effecting the repair of damaged DNA, and as a regulator of histone H2B transcription. 

TLS Online TPP Program

#Id: 366

#Unit 1. Structure and Function of Biomolecules

The enzyme that catalyzes this reversible reaction is called succinyl-CoA synthetase or succinic thiokinase


TLS Online TPP Program

#Id: 8674

#Unit 1. Structure and Function of Biomolecules