Because nucleosomal DNA wraps around the histone protein 1.65 times, the formation of a single nucleosome using ccc plasmid would create a writhe of –1.65 and thus change the linking number by an equivalent amount. As described above, when the change in linking number associated with each nucleosome was measured, the number was lower than this, approximately –1.2 for each nucleosome added.

This discrepancy is referred to as the “nucleosome linking  number paradox,”

TLS Online TPP Program

#Id: 3693

#Unit 2. Cellular Organization

The largest component of the human genome consists of transposons.

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#Id: 2872

#Unit 13. Methods in Biology

Algebraic transformation of the exponential correlation into an expression based on the decadic logarithm yields the law of Beer–Lambert:

where [d] = 1cm, [c] = 1moldm-3, and [e] = 1dm3mol-1 cm1. e is the molar absorption   coefficient.

where [d] = 1cm, [c] = 1moldm-3, and [e] = 1dm3mol-1 cm1. e is the molar absorption coefficient.

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#Unit 2. Cellular Organization

mtDNA is located in the mitochondrial matrix, and in the rapidly growing cells, mtDNA is often seen in regions devoid of densely stacked cristae.

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#Id: 406

#Unit 2. Cellular Organization

In yeast, centromeric nucleosomes consist of Cse4, H4, and a nonhistone protein Scm3, in place of H2A-H2B dimers.

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#Id: 6490

#Unit 3. Fundamental Processes

Strikingly, a number of TAFs resemble histones: nine of 14 TAPs contain a histone fold domain, though in most cases the TAFs lack the residues of this domain that are responsible for DNA binding.