Matrix-associated regions (MARs) may be identified by characterizing the DNA retained by the matrix isolated in vivo (left) or by identifying the fragments that can bind to the matrix from which all DNA has been removed (right).

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#Unit 4. Cell Communication and Cell Signaling

Granulocytes can be seen by FACS.

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#Unit 4. Cell Communication and Cell Signaling

Neutrophils constitute the majority (50% to 70%) of circulating leukocytes Eosinophils (1%–3%), Basophils (1%), or Mast cells (1%).

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#Unit 4. Cell Communication and Cell Signaling

The resulting transient increase in the number of circulating neutrophils, called leukocytosis.

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#Unit 4. Cell Communication and Cell Signaling

Neutrophils phagocytose (engulf) bacteria very effectively, and also secrete a range of proteins that have antimicrobial effects and tissue remodeling potential.

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#Unit 4. Cell Communication and Cell Signaling

Neutrophils- First cell against infection

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#Unit 4. Cell Communication and Cell Signaling

Basophils are nonphagocytic granulocytes.