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TLS Online TPP Program

#Id: 4537

Recombinant vaccines


#Unit 12. Applied Biology #Vaccines #Part B Pointers
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TLS Online TPP Program

#Id: 10085

#Unit 4. Cell Communication and Cell Signaling

I-domains also recognize CAMs on other cells, 
ICAMs, VCAMs and participate in cell-cell adhesion.
TLS Online TPP Program

#Id: 10086

#Unit 4. Cell Communication and Cell Signaling

The non-I-domain α subunits recognize RGD motif.
TLS Online TPP Program

#Id: 10087

#Unit 4. Cell Communication and Cell Signaling

TGF-β1 and TGF-β3 contain RGD motif that binds to integrins.
TLS Online TPP Program

#Id: 10088

#Unit 4. Cell Communication and Cell Signaling

Integrins typically exhibit low affinities for their ligands, with dissociation constants (Kd) between 10−6 and 10−7 mol/L.
TLS Online TPP Program

#Id: 10089

#Unit 4. Cell Communication and Cell Signaling

Integrins are involved in biological activities, includes: 
Extravasation
Cell-to-cell adhesion
Cell migration
Receptors for certain viruses
Angiogenesis
Apoptosis
TLS Online TPP Program

#Id: 10090

#Unit 4. Cell Communication and Cell Signaling

Integrins can mediate outside-in and inside-out signaling