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If cells that have incorporated a high level of BrdU are exposed to light, they will photolyse; this has been used to selectively kill newly dividing cells.


#Unit 13. Methods in Biology #Immunotechniques #Part B Pointers
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#Unit 5. Developmental Biology


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#Unit 5. Developmental Biology


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#Unit 5. Developmental Biology

IFN- ¥ has been shown to induce expression of the class II transcriptional activator (CIITA). 

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#Unit 5. Developmental Biology

IL-4 increases expression of class II molecules in resting B cells, turning them into more efficient APCs.

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#Unit 5. Developmental Biology

Expression of class II molecules by B cells is down-regulated by IFN-¥. 

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#Unit 5. Developmental Biology

Corticosteroids and prostaglandins can also decrease expression of class II MHC molecules.

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