When the p-value is less than the level of significance (α), the null hypothesis is rejected. If the p-value so observed is not less than the significance level α, then theoretically null hypothesis is accepted.

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#Unit 8. Inheritance Biology

DOWN SYNDROME Also known as trisomy 21, is the most common autosomal aneuploidy in humans About 75% of the nondisjunction events that cause Down syndrome are maternal in origin, most arising in meiosis I. 

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#Unit 8. Inheritance Biology

Those who have Down syndrome have three full copies of chromosome 21, a condition termed primary Down syndrome.

familial Down syndrome Human condition caused by a Robertsonian translocation in which the long arm of chromosome 21 is translocated to another chromosome; tends to run in families.

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#Unit 8. Inheritance Biology

TLS Online TPP Program

#Id: 6977

#Unit 8. Inheritance Biology

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#Unit 8. Inheritance Biology

HUMAN TRISOMIES

Trisomy 18 - Edward syndrome

Trisomy 13 - Patau syndrome. 

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#Unit 8. Inheritance Biology

Uniparental Disomy Inheritance of both chromosomes of a homologous pair from a single parent.  Many cases of uniparental disomy probably originate as trisomies.