The sensory nerves from mechanoreceptors are large myelinated Aα and Aβ fibers whose conduction velocities range from ∼70–120 & ∼40–75 m/s, respectively.

TLS Online TPP Program

#Id: 1307

#Unit 2. Cellular Organization

Nucleotide binding domain serves as a built-in protein kinase that functions to phosphorylate the P domain.

TLS Online TPP Program

#Id: 1308

#Unit 2. Cellular Organization

Actuator domain has protein phosphatase activity and removes the phosphoryl group from the Asp residue

TLS Online TPP Program

#Id: 1309

#Unit 2. Cellular Organization

E1’s ion-binding sites are exposed to the cytoplasm, and it has high affinity for Na+ but low affinity for K+

TLS Online TPP Program

#Id: 1310

#Unit 2. Cellular Organization

E1’s ion-binding sites are exposed to the cytoplasm, and it has high affinity for Na+ but low affinity for K+

TLS Online TPP Program

#Id: 1311

#Unit 2. Cellular Organization

E2’s ion binding sites are exposed to the exterior of the cell and it has low affinity for Na+ but high affinity for K+

TLS Online TPP Program

#Id: 1312

#Unit 2. Cellular Organization

Cardiac glycosides (e.g., ouabain and digitalis) are a class of drugs that inhibits Na+-K+ ATPase.