The MutT, -M, -Y system handles the consequences of oxidative damage. Major type of chemical damage is caused by oxidation of G to 8-oxo-G

TLS Online TPP Program

#Id: 6681

#Unit 3. Fundamental Processes

Each snRNP contains a single snRNA (100-300 nt) and several (20) proteins. The U4 and U6 snRNPs are usually found together as a di-snRNP (U4/U6) particle.

TLS Online TPP Program

#Id: 6682

#Unit 3. Fundamental Processes

U1 snRNA consist of four hairpins, one intron pairing strands and one sm binding domains.

TLS Online TPP Program

#Id: 6683

#Unit 3. Fundamental Processes

More than 90% of the genes expressed in mammals are alternatively spliced

TLS Online TPP Program

#Id: 6684

#Unit 3. Fundamental Processes

Five ways to splice an RNA

TLS Online TPP Program

#Id: 6685

#Unit 3. Fundamental Processes

Steric Hindrance and Combinations of Major and Minor Splice Sites are major reasons behind alternative splicing (Mutually Exclusive Splicing) 

TLS Online TPP Program

#Id: 6686

#Unit 3. Fundamental Processes

Alternative splicing is often associated with weak splice sites.