TLS Online TPP Program

#Id: 6423


Autosomal dominant 
Traits appear in both sexes with equal frequency.
Both sexes are capable of transmitting these traits to their offspring.
An affected person has an affected parent (unless the person carries new mutations). 
The trait does not skip generations.
Unaffected people do not transmit the trait. 
Example- familial hypercholesterolemia, Huntington disease, Neurofibromatosis




#Unit 8. Inheritance Biology #Human genetics #Part B Pointers
More Pointers
TLS Online TPP Program

#Id: 9939

#Unit 4. Cell Communication and Cell Signaling

Tuberculosis
Tuberculosis, caused by Mycobacterium tuberculosis.
Pulmonary infection usually results from inhalation of small droplets of respiratory secretions containing a few bacilli.

TLS Online TPP Program

#Id: 9940

#Unit 4. Cell Communication and Cell Signaling

The inhaled bacilli are ingested by alveolar macrophages in the lung and inhibiting formation of phagolysosomes

CD4+ T cells are activated within 2 to 6 weeks after infection.

TLS Online TPP Program

#Id: 9941

#Unit 4. Cell Communication and Cell Signaling

These cells wall off the organism inside a granuloma called a tubercle. The localized concentrations of lysosomal enzymes in these granulomas can cause extensive tissue necrosis.

TLS Online TPP Program

#Id: 9942

#Unit 4. Cell Communication and Cell Signaling

Diphtheria

Natural infection with C. diphtheriae occurs only in humans and is spread by respiratory droplets. 

The organism colonizes the nasopharyngeal tract and causes little tissue damage, with only a mild inflammatory reaction. 

TLS Online TPP Program

#Id: 9943

#Unit 4. Cell Communication and Cell Signaling

Virulence is due to its potent exotoxin, which destroys the underlying tissue and results in heart, liver, and kidney damage, as well as to suffocation following formation of a tough fibrous membrane in the respiratory tract

TLS Online TPP Program

#Id: 9944

#Unit 4. Cell Communication and Cell Signaling

Malaria (Parasitic)

Sporozoites enter the bloodstream by mosquito.

The sporozoites migrate to the liver, where they multiply, transforming liver hepatocytes into giant multinucleate schizonts, which release thousands of merozoites into the bloodstream.