Autosomal dominant 

Traits appear in both sexes with equal frequency.

Both sexes are capable of transmitting these traits to their offspring.

An affected person has an affected parent (unless the person carries new mutations). 

The trait does not skip generations.

Unaffected people do not transmit the trait. 

Example- familial hypercholesterolemia, Huntington disease, Neurofibromatosis

TLS Online TPP Program

#Id: 5465

#Unit 7. System Physiology – Animal

p75 NTR forms heteromeric complexes with the different Trk receptors and enhances Trk receptor signaling

TLS Online TPP Program

#Id: 5466

#Unit 7. System Physiology – Animal

Schwann cells and astrocytes produce ciliary neurotrophic factor which promotes the survival of damaged and embryonic spinal cord neurons

TLS Online TPP Program

#Id: 5467

#Unit 7. System Physiology – Animal

A synapse is a site where information is transmitted from one cell to another. 

Types of synapses:

1. electrical synapse

2. chemical synapse

TLS Online TPP Program

#Id: 5468

#Unit 7. System Physiology – Animal

Principle of one-way conduction at chemical synapses 

always transmit the signals in one direction i.e., from the neuron that secretes the neurotransmitter called the presynaptic neuron, to the neuron on which the transmitter acts, called the postsynaptic neuron

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#Id: 5469

#Unit 7. System Physiology – Animal

Once an impulse reaches the presynaptic terminals, a response can be obtained in the postsynaptic neuron after a Synaptic delay.

TLS Online TPP Program

#Id: 5470

#Unit 7. System Physiology – Animal

Synaptic delay is due to the time it takes for the synaptic mediator to be released and to act on the receptors on the membrane of the postsynaptic cell. 

The minimum time for synaptic delay is 0.5 ms