TFIIB, TFIIE, and TFIIH are required to melt DNA to allow polymerase movement. The last factors to join the initiation complex are TFIIE and TFIIH. 

TLS Online TPP Program

#Id: 6517

#Unit 7. System Physiology – Animal

Phenylethanolamine-N-methyltransferase catalyzes the formation of epinephrine from norepinephrine, is found in appreciable quantities only in the brain and the adrenal medulla

TLS Online TPP Program

#Id: 6518

#Unit 7. System Physiology – Animal

Adrenal medullary PNMT is induced by glucocorticoids

TLS Online TPP Program

#Id: 6519

#Unit 7. System Physiology – Animal

Glucocorticoids are apparently necessary for the normal development of the adrenal medulla

TLS Online TPP Program

#Id: 6520

#Unit 7. System Physiology – Animal

In 21β-hydroxylase deficiency, glucocorticoid secretion is reduced during fetal life and the adrenal medulla is dysplastic

TLS Online TPP Program

#Id: 6521

#Unit 7. System Physiology – Animal

Reuptake of Norepinephrine via aNET (norepinephrine transporter) is a major mechanism to terminate the actions of norepinephrine.

TLS Online TPP Program

#Id: 6522

#Unit 7. System Physiology – Animal

Epinephrine and norepinephrine are metabolized to biologically inactive products by oxidation & methylation catalyzed by monoamine oxidase and catechol -O- methyltransferase respectively