Nurturing Life Sciences
#Id: 6585
#Id: 792
#Unit 3. Fundamental Processes
#Id: 793
Rho is a member of the family of hexameric ATP-dependent helicases. Each subunit has an RNA-binding domain and an ATP hydrolysis domain.
#Id: 794
Rho activity is impeded when ribosomes are translating an mRNA.
#Id: 795
The action of rho factor may create link between transcription and translation when a rho-dependent terminator lies soon after a nonsense mutation.
#Id: 796
Nonsense mutation in one gene of a transcription unit was found to prevent the expression of subsequent genes in the unit even though both genes had their own ribosome binding sites, an effect called polarity.
#Id: 797
There are proteins so-called nut sites in the leader regions of both the 16S and 23S rRNA transcripts, forming antitermination complexes that inhibit the action of rho.