Extensive shortening of telomeres is recognized by the cell as a double-strand break and consequently triggers cell cycle arrest and apoptosis.

TLS Online TPP Program

#Id: 3197

#Unit 4. Cell Communication and Cell Signaling

Dominant gain-of-function mutations in proto-oncogenes and recessive loss-of-function mutations in tumor-suppressor genes are oncogenic.

TLS Online TPP Program

#Id: 6729

#Unit 8. Inheritance Biology

TLS Online TPP Program

#Id: 4712

#Unit 13. Methods in Biology

The electronic transitions of the peptide bond occur in the far UV. The intense peak at 190 nm, and the weaker one at 210–220 nm is due to the p!p* and n!p* transitions.

TLS Online TPP Program

#Id: 2337

#Unit 3. Fundamental Processes

DskA is required for the regulation of rrn  transcription by these two small molecules. Indeed, rrn  transcription is insensitive to iNTP and ppGpp in mutants lacking DskA.

TLS Online TPP Program

#Id: 3820

#Unit 5. Developmental Biology

The top of the mound continues to emit cAMP pulses and is pushed upwards by the movement of cells underneath