crRNA and Cascade are then directed to and cleave the target DNA with the help of Cas3 in E.coli

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#Unit 5. Developmental Biology

In the absence of Cerberus, Nodal is not activated and thus Pitx2 is not expressed

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#Unit 5. Developmental Biology

Drosophila eggs undergo Superficial cleavage.

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#Unit 5. Developmental Biology

In the Drosophila egg, karyokinesis occurs without cytokinesis to create a syncytium.

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#Unit 5. Developmental Biology

In Drosophila, during the ninth division cycle- Pole cells determination 

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#Unit 5. Developmental Biology

The transition from specification to determination in Drosophila is mediated by Segmentation genes.

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#Unit 5. Developmental Biology

First zygotic genes is Gap genes. Mutations in them cause gaps in the segmentation pattern.