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TLS Online TPP Program

#Id: 7098


In about half the polypeptides, the methionine at the terminus is removed by an aminopeptidase, which creates a new terminus from R2 (originally the second amino acid incorporated into the chain). When both steps are necessary, they occur sequentially. The removal reaction(s) occur rather rapidly when the nascent polypeptide chain has reached a length of 15 amino acids.

#Unit 3. Fundamental Processes #Prokaryotic Translation #Part B Pointers
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TLS Online TPP Program

#Id: 9710

#Unit 4. Cell Communication and Cell Signaling

Cdc24 = SOS
Cdc42 = Ras

TLS Online TPP Program

#Id: 9711

#Unit 4. Cell Communication and Cell Signaling

GTP-bound Cdc42, binds to and activates the Ste20 kinase.

TLS Online TPP Program

#Id: 9712

#Unit 4. Cell Communication and Cell Signaling

Ste20 serves as a MAPKKK kinase.


TLS Online TPP Program

#Id: 9713

#Unit 4. Cell Communication and Cell Signaling

Ste20 phosphorylates and activates Ste11, a serine/threonine kinase

TLS Online TPP Program

#Id: 9714

#Unit 4. Cell Communication and Cell Signaling

Ste11 analogous to Raf and other mammalian MEK kinase (MEKK) proteins.

TLS Online TPP Program

#Id: 9715

#Unit 4. Cell Communication and Cell Signaling

Activated Ste11 then phosphorylates Ste7, a dual-specificity MEK.

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