When pairs of human 23 and mouse 20 homologs are compared, the genes located on either side also tend to be homologs. This relationship is called synteny

TLS Online TPP Program

#Id: 680

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 681

#Unit 3. Fundamental Processes

Cdc13 is a positive activator of telomerase

TLS Online TPP Program

#Id: 682

#Unit 3. Fundamental Processes

Cdc13 binds to the single-stranded telomere repeat DNA and is involved in telomerase recruitment.

TLS Online TPP Program

#Id: 683

#Unit 3. Fundamental Processes

POT1 binding to single-stranded telomere DNA inhibits telomere activity.

TLS Online TPP Program

#Id: 684

#Unit 3. Fundamental Processes

Structure of growing Telomere is potential target for DSBR

TLS Online TPP Program

#Id: 685

#Unit 3. Fundamental Processes

Attempts to repair telomeres in the DSBR manner as double-stranded DNA breaks would lead to chromosome fusion events, which eventually result in random chromosome breaks.