Nurturing Life Sciences
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#Unit 5. Developmental Biology
A fruit fly’s sex is determined predominantly by the number of X chromosomes in each cell.
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A fly have two X chromosomes and three sets of autosomes, it is a mosaic.
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Three major RNA targets to which the female-specific Sxl transcript binds:
Pre-mRNA of Sxl itself
msl2 gene
pre-mRNA of transformer (tra)
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The Drosophila doublesex (dsx) gene is active in both males and females, but its primary transcript is processed in a sex-specific manner.
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