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#Unit 6. System Physiology – Plant #BR #Part B Pointers
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#Unit 7. System Physiology – Animal


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#Unit 7. System Physiology – Animal

Myocardial fibers have a resting membrane potential of approximately –90 mV.


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#Unit 7. System Physiology – Animal

The individual fibers are separated by membranes, but depolarization spreads radially (syncytium) because of the presence of gap junctions.


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#Unit 7. System Physiology – Animal

In cardiac muscle, the action potential is caused by opening of three types of channels

Voltage activated fast sodium channels 

L-type calcium channels (slow calcium channels or calcium-sodium channels)

Voltage activated potassium ion channels



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#Unit 7. System Physiology – Animal

Phase 0 (depolarization), fast sodium channels open. 


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#Unit 7. System Physiology – Animal

Phase 1 (initial repolarization), fast sodium channels close


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