A rut site has a sequence rich in C -41% and poor in G preceding the actual site(s) of termination. The sequence corresponds to the 3’ end of the RNA.

 

TLS Online TPP Program

#Id: 9996

#Unit 4. Cell Communication and Cell Signaling

In Wnt-Ca2+ pathway, Wnt binding to the receptor protein possibly Ryk, alone or in concert with Frizzled.

TLS Online TPP Program

#Id: 9997

#Unit 4. Cell Communication and Cell Signaling

Frizzled-G protein signaling activates PLC-beta, which cleaves PIP2 into DAG and IP3.

TLS Online TPP Program

#Id: 9998

#Unit 4. Cell Communication and Cell Signaling

Wnt/calcium pathway leads to the release of calcium stored within cells, and calcium acts as an important secondary messenger to modulate the function of many downstream targets.

TLS Online TPP Program

#Id: 9999

#Unit 4. Cell Communication and Cell Signaling

Increased Ca2+ levels activates Ca2+-dependent signaling molecules such as:

Protein kinase C, Ca2+/calmodulin-dependent protein kinase (CamKII), Calcineurin phosphatase

TLS Online TPP Program

#Id: 10000

#Unit 4. Cell Communication and Cell Signaling

Calcineurin phosphatase, dephosphorylates and activates the transcription factor, Nuclear Factor Associated with T cells (NFAT).

TLS Online TPP Program

#Id: 10001

#Unit 4. Cell Communication and Cell Signaling

Vertebrates have three homologues of the Drosophila hedgehog gene: sonic hedgehog (shh), desert hedgehog

(dhh), and indian hedgehog (ihh)