Nurturing Life Sciences
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#Unit 3. Fundamental Processes
Each Okazaki fragment starts with a primer sequence of RNA 10 bases long that provides the 3’–OH end for extension by DNA polymerase
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The DnaG primase is an RNA polymerase is smaller than RNA Polymerase; and synthesizes short stretches of RNA that are used as primers for DNA synthesis.
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DnaG primase associates transiently with the replication complex, and typically synthesizes a 10-base primer. Primers start with the sequence pppAG positioned opposite the sequence 3’–GTC-5’ in the template.
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Replicons are referred to as being of the PhiX or oriC type.
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