Monotelic attachment 

only one kinetochore can attach to microtubules

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#Id: 5426

#Unit 7. System Physiology – Animal

In the CNS of mammals, most neurons are myelinated, but the cells that form the myelin are oligodendrocytes rather than Schwann cells

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#Id: 5427

#Unit 7. System Physiology – Animal

In multiple sclerosis, a crippling autoimmune disease, patchy destruction of myelin occurs in the CNS

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#Id: 5428

#Unit 7. System Physiology – Animal

Orthograde transport

moves from the cell body toward the axon terminals 

occurs along microtubules that run along the length of the axon and requires dynein and kinesin

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#Id: 5429

#Unit 7. System Physiology – Animal

Orthograde transport has:

Fast axonal transport occurs at about 400 mm/day 

Slow axonal transport occurs at 0.5 to 10 mm/day

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#Id: 5430

#Unit 7. System Physiology – Animal

Retrograde transport, is in the opposite direction (from the nerve ending to the cell body), occurs along microtubules at about 200 mm/day.

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#Id: 5431

#Unit 7. System Physiology – Animal

Two types of potentials are produced:

Nonpropagated potentials (local), depending on their location, synaptic, generator, or electrotonic potentials

Propagated potentials, the action potentials (or nerve impulses)