Centralspindlin is a heterotetramer composed of two copies of the kinesin-6 motor protein MKLP1 and a dimer of a Rho GAP

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#Id: 1243

#Unit 7. System Physiology – Animal

FSH & LH control growth of the ovaries and testes.

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#Id: 1244

#Unit 7. System Physiology – Animal

GHRH- Hypothalamus stimulates growth hormone secretion by utilizing both cAMP and IP3/Ca2+ as second messengers.

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#Id: 1245

#Unit 7. System Physiology – Animal

Somatotropes—human growth hormone promotes growth of the entire body by affecting protein formation, cell multiplication, and cell differentiation.

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#Id: 1246

#Unit 7. System Physiology – Animal

Somatostatin (somatotropin release–inhibiting hormone) –hypothalamus Inhibit growth hormone secretion.

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#Id: 1247

#Unit 7. System Physiology – Animal

Somatostatin binds membrane receptor, which is coupled to Galpha i protein.

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#Id: 1248

#Unit 7. System Physiology – Animal

Before puberty, growth hormone excess causes gigantism