Centralspindlin-Ect2 complex catalyzes activation of RhoA, leading to cleavage furrow formation and division of the cytoplasm to form two completely separate cells.

TLS Online TPP Program

#Id: 8504

#Unit 1. Structure and Function of Biomolecules

Domain

Domains are formed by combinations of SS, SSS, motifs and connected by loops and turns.

Highly conversed and may be common in most unrelated proteins

They evolve

Can function Independently

Average 100 amino acids 

Single hydrophobic core

TLS Online TPP Program

#Id: 8505

#Unit 1. Structure and Function of Biomolecules

24 possible ways in which two adjacent ~ hairpin motifs, each consisting of two antiparallel ~ strands connected by a loop region, can be combined to make a more complex motif.

TLS Online TPP Program

#Id: 8506

#Unit 1. Structure and Function of Biomolecules

TLS Online TPP Program

#Id: 8507

#Unit 1. Structure and Function of Biomolecules

TLS Online TPP Program

#Id: 8508

#Unit 1. Structure and Function of Biomolecules

Structural Classification of Proteins database =SCOP

TLS Online TPP Program

#Id: 8509

#Unit 1. Structure and Function of Biomolecules

CATH differs from SCOP in that it combines manual analysis with automation based on quantitative algorithms to classify protein structures.