If the duplicate is redundant and does not provide a fitness benefit, it will be lost by deletion or the accumulation of loss of-function mutations.

A second fate is that a duplicate can simply retain its original function.

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#Id: 9891

#Unit 4. Cell Communication and Cell Signaling

Pattern recognition receptors (PRRs)

Receptors of the innate immune system that recognize molecular patterns or motifs present on pathogens but absent in the host.

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#Id: 9892

#Unit 4. Cell Communication and Cell Signaling

Pattern recognition

Families of PRRs (TLRs, CLRs, RLRs, and NLRs) recognize a wide variety of PAMP (and DAMP) ligands.

TLS Online TPP Program

#Id: 9893

#Unit 4. Cell Communication and Cell Signaling

Toll-Like Receptors Recognize Many Types of Pathogen Molecules - Vertebrate Toll-like receptors  are dimers of chains with extracellular leucine-rich (LRR) domains that bind PAMPs and DAMPs. 

TLS Online TPP Program

#Id: 9894

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 9895

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 9896

#Unit 4. Cell Communication and Cell Signaling