Nurturing Life Sciences
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#Unit 5. Developmental Biology
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The highly proliferative mesenchyme that fuels limb bud growth is known as the progress zone mesenchyme
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Fgf10 is the major active factor in the PZ.
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The cells found within the most posterior region of the progress zone constitute the zone of polarizing activity.
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Sonic hedgehog, is the major active factor in the ZPA.
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The apical ectodermal ridge is a thickening of the ectoderm at the apex of the developing limb bud.