Smad7 binds to the activated RI receptors and blocks its ability to phosphorylate Smad2 or Smad3. 

TLS Online TPP Program

#Id: 624

#Unit 2. Cellular Organization

Dual hairpin formation (Region 3-4 forms hairpin then second hairpin is formed between Region 1-2) release RNA-DNA hybrid and RNA Polymerase causes seizing transcription of trp operon at high trp concentration.

TLS Online TPP Program

#Id: 625

#Unit 2. Cellular Organization

Attenuator riboswitch (Leader sequence) region 1 is translated atleast till codon 10 and 11 in case of Low trp concentration because ribosomes get stalled due to low availability of charged tRNA-trp

TLS Online TPP Program

#Id: 626

#Unit 2. Cellular Organization

In case of Low trp concentration, RNA polymerase continues to EDCBA genes where new ribosome get attached to AUG of polycistronic genes

TLS Online TPP Program

#Id: 627

#Unit 2. Cellular Organization

RNA Polymerase don’t get dissociated with one hairpin which is 2:3 

TLS Online TPP Program

#Id: 628

#Unit 2. Cellular Organization

Transcription is initiated at the beginning of the 162 nucleotide mRNA leader encoded by a DNA region called trpL.

TLS Online TPP Program

#Id: 3501

#Unit 2. Cellular Organization

Interrupted genes are longer than its mature RNA product because of the presence of the introns hence Length of precursor RNA (not mRNA) defines region of gene