Polygynous

In polygyny, one male mates with more than one female in a single breeding season, but females mate only with one male.

In species with male-male competition, males are often substantially larger than females, a phenomenon called sexual dimorphism.

TLS Online TPP Program

#Id: 9957

#Unit 4. Cell Communication and Cell Signaling

Wnts are paracrine factors that make up a large family of cysteine-rich glycoproteins

TLS Online TPP Program

#Id: 9958

#Unit 4. Cell Communication and Cell Signaling

Structure of Wnt proteins 

22 cysteine residues, which form disulfide bridges that maintain a globular secondary structure.

TLS Online TPP Program

#Id: 9959

#Unit 4. Cell Communication and Cell Signaling

Wnt = wingless + integrated

TLS Online TPP Program

#Id: 9960

#Unit 4. Cell Communication and Cell Signaling

Wnt proteins are modified by linkage of a monounsaturated fatty acid, palmitoleic acid, to a serine in the middle of the protein.

TLS Online TPP Program

#Id: 9961

#Unit 4. Cell Communication and Cell Signaling

Lipid modifications of Wnt are catalyzed by the 

O-acetyltransferase Porcupine.

TLS Online TPP Program

#Id: 9962

#Unit 4. Cell Communication and Cell Signaling

Principal signaling receptor is Frizzled (Fz), contains 

7 TM α helices.