#Question id: 4533
#Unit 3. Fundamental Processes
When multiple activators work together, they often do so synergistically. That is, the effect of
#Question id: 4534
#Unit 3. Fundamental Processes
The yeast Saccharomyces cerevisiae divides by budding: instead of dividing to produce two identical daughter cells, the so-called mother cell buds to produce a daughter cell, The HO gene is expressed only in mother cells and only at a certain point in the cell cycle,
|
1. SBF |
I- Which is active only during the G1-S transition of the cell cycle. |
|
2. SWI5 |
II-Which acts only in the mother cell. |
|
III- Recruit nucleosome modifiers |
#Question id: 4535
#Unit 3. Fundamental Processes
The activators bind—and the enhanceosome forms—in a highly cooperative manner, ensuring that all three activators must be present. The following are three ways the regulators might be binding cooperatively:
I- Through direct protein–protein interactions between them
II- By changes in the DNA caused by binding of one protein helping binding of another;
III- By the fact that the activators all interact simultaneously with the coactivator.
#Question id: 4536
#Unit 3. Fundamental Processes
The human b-interferon gene is activated in cells upon viral infection through some activators, EXCEPT one
#Question id: 4537
#Unit 3. Fundamental Processes
The enhancer DNA is __, but once the activators are bound it is relatively , HMGA1 the DNA and thus helps the final structure form.
#Question id: 4538
#Unit 3. Fundamental Processes
We first consider a generic case. Gene A is controlled by four signals (1, 2, 3, and 4), each working through a separate activator (activators 1, 2, 3, and 4). Gene B is controlled by three signals (3, 5, and 6), working through activators 3, 5, and 6. It shows-