Which of the following mutations might confer a competitive advantage to an athlete by raising his or her hematocrit?

a. excess production of erythropoietin                       

b. decreased production of erythropoietin

c. EpoR that cannot bind STAT5                  

d. EpoR that cannot bind SHP1

e. EpoR that cannot bind JAK2

TLS Online TPP Program

#Question id: 15334

#Unit 4. Cell Communication and Cell Signaling

In which type of BCR (surface protein) present on to the B-cell, which are responsible for the conversion of membrane bound into secreted form of antibody. If it is not present then this conversion isn’t possible;

TLS Online TPP Program

#Question id: 15335

#Unit 4. Cell Communication and Cell Signaling

Some given following co-receptor present on to the B-cell surface except

TLS Online TPP Program

#Question id: 15336

#Unit 4. Cell Communication and Cell Signaling

Which of the following cell surface markers responsible for the regulation of B-cell ?

TLS Online TPP Program

#Question id: 15337

#Unit 4. Cell Communication and Cell Signaling

HSCs express which type of cell-surface molecule, which is the receptor for stem cell factor (SCF). It is a cytokine that exists in both membrane-bound and soluble forms and the SCF-surface molecules interaction is critical for the development, in adult animals, of multipotential progenitor cells (MPPs).  Which type of surface molecules HSCs express?

TLS Online TPP Program

#Question id: 15338

#Unit 4. Cell Communication and Cell Signaling

Which cell generated on the receipt of SCF/c-Kit signaling lose the capacity for extensive self-renewal, but retain the potential to differentiate into several different hematopoietic lineages and also transiently express the molecule CD34?

TLS Online TPP Program

#Question id: 15339

#Unit 4. Cell Communication and Cell Signaling

HSCs begin their life in close contact with osteoblasts located close to the lining of the endosteal cavity. Once differentiated to the pre-pro-B-cell stage, the developing B cells require Which type of signals from the chemokine, which is secreted by a specialized set of stromal cells?