Practice Questions

TLS Online TPP Program

#Question id: 18082

The interaction of selection and inbreeding in determining the incidence of autosomal recessive diseases. Consider a gene in which recessive mutations occur at a rate of 10^-5. Assume a selective disadvantage S of 0.4 in homozygotes for the recessive allele. Now assume that, for thousands of generations, 10% of all children have been products of first-cousin matings (the remaining 90% being products of random matings). Calculate the steady-state value of q. Also calculate the incidence of the disease at steady state.

#Unit 8. Inheritance Biology

0.00002574, incidence=1 in seventy thousand
0.0032, incidence=1 in twenty thousand
0.00284, incidence=1 in forty thousand
8.104 ×10^-6, incidence= 1 in fifty thousand

More Questions

TLS Online TPP Program

#Question id: 28760

#Unit 2. Cellular Organization

Pex5 is a receptor which binds with peroxisomal-targeting sequence proteins in the cytosol that protein targeted into the peroxisomal matrix by forming a multimeric complex with the Pex14 receptor located on the peroxisomal membrane. After assembly, the matrix protein dissociates from Pex5 and Pex5 is then returned to the cytosol by which process?

TLS Online TPP Program

#Question id: 518

#Unit 1. Molecules and their Interaction Relevant to Biology

Transfer of the phosphoryl group from PEP to ADP is an example of

TLS Online TPP Program

#Question id: 24489

#Unit 3. Fundamental Processes

Two transesterification reactions takes place for 2 exon -1 intron configuration. Choose the correct statement

a. First transesterification is always caused by exon 1 -3’OH

b. second transesterification is catalysed variably either by external G or branch point while .

c. First transesterification is catalysed variably either by external G or branch point while

d. second transesterification is always caused by exon 1 -3’OH.