TLS Online TPP Program

#Question id: 2014


Some pathogens can undergo rapid changes resulting in antigenic variation. Which of the following is such a pathogen?

#Unit 4. Cell Communication and Cell Signaling
  1. the influenza virus, which expresses alternative envelope proteins

  2. the strep bacteria, which can be communicated from patient to patient with high efficiency

  3. human papilloma virus, that can remain latent for several years

  4. the causative agent of an autoimmune disease such as rheumatoid arthritis

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TLS Online TPP Program

#Question id: 4078

#Unit 3. Fundamental Processes

Which of the following is (are) required for splicing to occur?

a. two transesterification reactions

b. intact, naturally occurring introns

c. formation of a lariat like structure

d. a branch-point G residue

TLS Online TPP Program

#Question id: 4079

#Unit 3. Fundamental Processes

What is the evidence that pre-mRNAs are not synthesized unless machinery for processing is properly positioned?

TLS Online TPP Program

#Question id: 4080

#Unit 3. Fundamental Processes

How the location of exons and introns within a gene are determined?

TLS Online TPP Program

#Question id: 4081

#Unit 3. Fundamental Processes

Which of the following regulatory scenarios of cell-type-specific expression of fibronectin isoforms in humans is (are) consistent with information on known splicing factors?

a. A Tra-like splicing factor expressed in fibroblasts is required for inclusion of EIIIA and EIIIB exons.

b. An Sxl-like splicing factor is required in hepatocytes for exclusion of EIIIA and EIIIB exons.

c. A Tra-2-like factor enhances binding of the cleavage/polyadenylation complex in fibroblasts.

d. A Dsx-like protein is required to inhibit transcription of the fibronectin gene.

TLS Online TPP Program

#Question id: 4082

#Unit 3. Fundamental Processes

Which of the following is (are) not involved in alternative splicing in eukaryotes?

TLS Online TPP Program

#Question id: 4083

#Unit 3. Fundamental Processes

Differential splicing of the Ca2+-activated K+ channel gene in ciliated neurons results in

a. hair cells with different response frequencies.

b. different channel isoforms.

c. channels that open at different calcium concentrations.

d. different channel mRNAs expressed in different cells.