TLS Online TPP Program

#Question id: 4341


Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the promoter for the lac operon to the region between the beta galactosidase (lacZ) gene and the permease (lacY) gene, which of the following results would be most likely?

#Unit 3. Fundamental Processes
  1. The three genes of the lac operon will be expressed normally.

  2. RNA polymerase will no longer transcribe permease.

  3. The operon will still transcribe the lacZ and lacY genes, but the mRNA will not be translated.

  4. Beta galactosidase will not be produced.

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TLS Online TPP Program

#Question id: 539

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following mutases catalyze the formation of a 2,3-BPG intermediate?

A) muscle phosphoglycerate mutases

B) plant phosphoglycerate mutases

C) yeast phosphoglycerate mutases

TLS Online TPP Program

#Question id: 540

#Unit 1. Molecules and their Interaction Relevant to Biology

During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD+ if glycolysis is to continue.  The most important reaction involved in the reoxidation of NADH is:

TLS Online TPP Program

#Question id: 541

#Unit 1. Molecules and their Interaction Relevant to Biology

The overall △G for glycolysis is -72 kJ/mol in erythrocytes. Which statement below is true?

A) The value of △G0ʹ is also -72 kJ/mol since the cytosol pH is close to 7.

B) The free energy of glycolysis is found as the sum of the standard free energy changes for

the individual pathway reactions.

C) The negative sign of △G shows that this pathway will proceed toward product (pyruvate) under normal cellular conditions.

TLS Online TPP Program

#Question id: 542

#Unit 1. Molecules and their Interaction Relevant to Biology

Hamsters love to run on exercise wheels. Prolonged running at a high rate of speed requires ATP. Could a hamster with a defective gene for the enzyme lactate dehydrogenase meet the extra ATP demand for prolonged, fast wheel-running by maintaining a high rate of glycolysis? Why or why not?

TLS Online TPP Program

#Question id: 543

#Unit 1. Molecules and their Interaction Relevant to Biology

If glucose labeled with 14C at C-1 (the aldehyde carbon) were metabolized in the liver, the first radioactive pyruvate formed would be labeled in:

TLS Online TPP Program

#Question id: 544

#Unit 1. Molecules and their Interaction Relevant to Biology

One of the enzymes involved in glycolysis, aldolase, requires Zn2+ for catalysis. Under conditions of zinc deficiency, when the enzyme may lack zinc, it would be referred to as the: