TLS Online TPP Program

#Question id: 7129


What is the developmental pathway by which the hematopoietic stem cell gives rise to a macrophage?

#Unit 5. Developmental Biology
  1. the hematopoietic stem cell divides, giving rise to a daughter cell that remains a stem cell and a daughter cell that differentiates directly into a macrophage.
  2. the hematopoietic stem cell can give rise to either a lymphoid progenitor or a myeloid progenitor; the myeloid progenitor differentiates directly into a macrophage.
  3. The hematopoietic stem cell can follow two paths, one called lymphoid and the other called myeloid, either of which can ultimately give rise to macrophages and other cell types such as osteoclasts and T cells.
  4. the hematopoietic stem cell must first generate a cell of the myeloid lineage (as opposed to the lymphoid lineage), then a granulocyte/macrophage progenitor, then a monocyte, and finally a macrophage.
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TLS Online TPP Program

#Question id: 33526

#Unit 2. Cellular Organization

The number of protein-coding genes is less than the number of potential polypeptides that can result in several polypeptides from the same gene because of mechanisms 
A. alternative splicing
B. alternate promoter selection, 
C. alternate poly(A) site selection
D. Number of Introns in the gene

TLS Online TPP Program

#Question id: 33527

#Unit 2. Cellular Organization

Match the following

TLS Online TPP Program

#Question id: 33528

#Unit 2. Cellular Organization

The Y chromosome has 

TLS Online TPP Program

#Question id: 33529

#Unit 2. Cellular Organization

A. X and Y chromosomes have descended from a common, very ancient autosome pair. 
B. X and Y chromosomes have descended from different autosome. 
C. During evolution, the X chromosome has retained most of the original genes, whereas the Y chromosome has lost most of them.
D. During evolution, the X chromosome has lost most of them, whereas the Y chromosome has retained most of the original genes.

Which of the following is correct combination

TLS Online TPP Program

#Question id: 33530

#Unit 2. Cellular Organization

One approach to determine the number of essential genes
A. Mutational Analysis
B. Sequence Alignments
C. Complementation
D. Mass Spectroscopy

TLS Online TPP Program

#Question id: 33531

#Unit 2. Cellular Organization

The data obtained during DNA microarray analysis showing wildtype vs. mutant expression of genes under different conditions, represented as