A. Trypsin treated core histones quickly forms 30-nm fibers

B. Core histones lacking their amino-terminal tails are incapable of forming 30-nm fibers

C. Interaction between the positively charged amino terminus of histone H4 and a negatively charged region of the histone-fold domain of histone H2A is particularly important for 30-nm fiber formation

D. H2A that interact with the H4 tail are conserved across many eukaryotic organisms but are not involved in DNA binding or formation of the histone octamer.

Choose true and false

TLS Online TPP Program

#Question id: 14884

#Unit 4. Cell Communication and Cell Signaling

Which types of cell shows the middle affinity towards the self proteins? 

TLS Online TPP Program

#Question id: 14885

#Unit 4. Cell Communication and Cell Signaling

Mature T cell is found in thymus in

TLS Online TPP Program

#Question id: 14886

#Unit 4. Cell Communication and Cell Signaling

Secondary lymphoid organ provide sites where lymphocytes encounter antigen, become activated, and undergo clonal expansion and differentiation into effector cells, include

a) spleen

b) lymph node

c) mucosa-associated lymphoid tissue

Which of the following are the effector cells of secondary lymphoid organ?

TLS Online TPP Program

#Question id: 14887

#Unit 4. Cell Communication and Cell Signaling

Secondary lymphoid organ are typically compartmentalized into T-cell areas and B-cell areas, these cells activity are separated  into distinct microenvironments such as

a) T cells are found in the paracortex of the lymph nodes

b) B cells are organized into follicles cells

c) B cells are found in the periarteriolar sheath of the spleen.

d) T cells are found in the periarteriolar sheath of the spleen.

Which of the following is the correct microenvironments of the cells ?

TLS Online TPP Program

#Question id: 14888

#Unit 4. Cell Communication and Cell Signaling

Given below are some cytokines and stimulated cell lines ;

CYTOKINE	CELL LINES STIMULATED
A) IL-1	i) Basophils
B) IL-4	ii) Myeloid lineages
C) IL-5	iii) Platelets
D) IL-6	iv) Megakaryocyte
E) Thrombopoietin	v) Eosinophill

Which one of the following is the correct match between the Interleukines and cell lines ?

TLS Online TPP Program

#Question id: 14889

#Unit 4. Cell Communication and Cell Signaling

If we provide  the Ikaros signals to the HSCs cell  is converted into