A. Trypsin treated core histones quickly forms 30-nm fibers

B. Core histones lacking their amino-terminal tails are incapable of forming 30-nm fibers

C. Interaction between the positively charged amino terminus of histone H4 and a negatively charged region of the histone-fold domain of histone H2A is particularly important for 30-nm fiber formation

D. H2A that interact with the H4 tail are conserved across many eukaryotic organisms but are not involved in DNA binding or formation of the histone octamer.

Choose true and false

TLS Online TPP Program

#Question id: 19114

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                                       

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR42 in Family 1.

TLS Online TPP Program

#Question id: 19115

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR43 in Family 1.

TLS Online TPP Program

#Question id: 19116

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                             

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR42 in Family 2.

TLS Online TPP Program

#Question id: 19117

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

 

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR43 in Family 2.

TLS Online TPP Program

#Question id: 19118

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                               

Calculate LOD scores for linkage at θ= 0.02 between SSR42 and SSR43 in Family 1.

TLS Online TPP Program

#Question id: 19119

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                     

Calculate LOD scores for linkage at θ= 0.02 between SSR42 and SSR43 in Family 2.