TLS Online TPP Program

#Question id: 613


Ethanol (CH3CH2OH) is the alcohol found in beverages. It is oxidized in the body to acetaldehyde by the enzyme alcohol dehydrogenase. Methanol (CH3OH), also known as wood alcohol, is converted to formaldehyde by the same enzyme. Acetaldehyde is toxic, but formaldehyde is far more toxic to humans, which is why the ingestion of relatively small amounts of methanol can cause blindness or death. One treatment for mild methanol poisoning is the administration of ethanol. Why might a doctor choose this treatment?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Ethanol must act as a competitive inhibitor for the alcohol dehydrogenase and therefore slows the formation of formaldehyde.

  2. Ethanol likely irreversibly binds to alcohol dehydrogenase which prevents the formation of formaldehyde.

  3. The ethanol is likely an uncompetitive inhibitor and binds to a site other than the active site of the enzyme.

  4. The doctor has given up on the patient and administers ethanol for sedation.

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TLS Online TPP Program

#Question id: 5138

#Unit 5. Developmental Biology

When presomitic mesoderm (PSM) that would ordinarily form thoracic somites is transplanted into a region in a younger embryo (caudal to the first somite) that would ordinarily give rise to cervical (neck) somites, the grafted mesoderm differentiates according to its original position and forms ribs in the neck. This phenomena is called as:

TLS Online TPP Program

#Question id: 5139

#Unit 5. Developmental Biology

There are two broad categories of receptors that activate tyrosine kinases: (1) those in which the tyrosine kinase enzyme is an intrinsic part of the receptor’s polypeptide chain, called the_________ and (2) those, in which the receptor and kinase are separate polypeptides, encoded by different genes, yet are bound tightly together, called the __________.

TLS Online TPP Program

#Question id: 5140

#Unit 5. Developmental Biology

Following statements regarding to the Ectodermal competence and the ability to respond to the optic vesicle inducer in Xenopus.

A. The optic vesicle is able to induce lens formation in the posterior portion of the ectoderm but not in the anterior portion.

B. If the optic vesicle is removed, the surface ectoderm forms either an abnormal lens or no lens at all.

C. Only head ectoderm is competent to respond to the signals from the optic vesicle by producing a lens.

D. The head ectoderm appears to secrete two paracrine factors BMP 4 and FGF8, which involves in the activation of lens-specific genes such as crystallin.

Which of the following combination is incorrect?

TLS Online TPP Program

#Question id: 5141

#Unit 5. Developmental Biology

Which of the following statement not describe the concept of morphogenetic gradient?

TLS Online TPP Program

#Question id: 5142

#Unit 5. Developmental Biology

The D set of blastomeres is the “organizer” of snail embryos. Experiments have demonstrated that the non-diffusible polar lobe [cortical] cytoplasm that is localized to the D blastomere is extremely important in normal molluscan development.  Which of the following is incorrect?

TLS Online TPP Program

#Question id: 5143

#Unit 5. Developmental Biology

Select the correct sequence of events in photoreceptor induction in drosophila.

A. Morphogenetic furrows moves across eye disc

B. Eyeless gene expression

C. R8 photoreceptor cells develop

D. R7 photoreceptor cells develop