The processes by which the three ectodermal regions are made physically and functionally distinct from one another is called neurulation. Following statements are regarding to the mechanism of neurulation.

A. The specification of the ectoderm is accomplished during gastrulation, primarily by regulating the levels of BMP experienced by the ectodermal cells.

B. High levels of BMP specify the cells to become neural plate.

C. Very low levels specify the cells to become epidermis.

D. Intermediate levels effect the formation of the neural crest cells.

Which of the following combination is correct?

#Question id: 910

#Unit 1. Molecules and their Interaction Relevant to Biology

Experiments on denaturation and renaturation after the reduction and reoxidation of the —S—S— bonds in the enzyme ribonuclease (RNase) have shown that:

#Question id: 911

#Unit 1. Molecules and their Interaction Relevant to Biology

The correct order for molecular chaperone–mediated protein folding is:

I – exchange of ATP for ADP on chaperone

II – chaperone undergoes conformational change, which affects protein folding

III – chaperone binds to exposed hydrophobic residues on unfolded protein

IV – folded protein is released

#Question id: 912

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct about the native state of a protein

a. is unaffected by changes in temperature and pH.

b. corresponds to the highest Gibbs free energy state.

c. is determined by its primary amino acid sequence.

d. corresponds to the lowest entropic state.

#Question id: 913

#Unit 1. Molecules and their Interaction Relevant to Biology

The appropriate folding of a newly translated product is essential, and continual misfolding often leads to disease, especially in vertebrates. This misfolding, particularly in the situation of prion diseases, may be due to

#Question id: 914

#Unit 1. Molecules and their Interaction Relevant to Biology

Lipoprotein lipase acts in:

#Question id: 915

#Unit 1. Molecules and their Interaction Relevant to Biology

Free fatty acids in the bloodstream are: